• Terapevt Arkh · Jan 1998

    Comparative Study

    [Complex assessment of inhacort effectiveness in bronchial asthma].

    • I M Kakhnovskiĭ, V F Marinin, S V Arkhipova, L A Sorokina, and G K Makhnach.
    • Terapevt Arkh. 1998 Jan 1; 70 (9): 73-6.

    AimTo investigate efficiency of inhacort in long-term (6 months to 2 years) treatment of bronchial asthma (BA).Materials And Methods67 inpatients and 65 outpatients with moderate BA were divided into two groups. 96 patients of group 1 had received standard combined treatment without glucocorticosteroids (GCS), 36 patients of group 2 had received GCS. Inpatients were given inhacort in a dose 1000 micrograms/day, outpatients took inhacort in a daily dose 500 micrograms/day. The examination scheme included assessment of external respiration function (ERF), blood hydrocortisone, sputum rheology and diagnosis of candidosis.ResultsInhacort treatment has reduced frequency of asphyxia attacks 2.5-fold 30 and 25% of the patients stopped taking sympathomimetics and GCS, respectively. None of the patients had asphyxia as a status. ERF, sputum viscosity improved, hydrocortisone secretion was unchanged. Only 3.8% of the patients developed oral candidosis.ConclusionInhacort in a dose 1 mg controls BA. 73% of the patients treated outpatiently had no need in hospitalization.

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