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- F Sevenet, H Deramond, A Hadengue, N Casadevall, J Delamarre, and J P Capron.
- Services d'Hépato-gastroentérologie et de Radiologie A, CHU Nord, Amiens, France.
- Gastroenterology. 1989 Oct 1; 97 (4): 1019-21.
AbstractAlthough membranous obstruction of the inferior vena cava is frequently assumed to be a congenital defect, it has recently been hypothesized that it could be acquired and secondary to thrombosis at the ostium of hepatic veins. We report the case of a membranous obstruction of the inferior vena cava responsible for isolated hepatomegaly in a young Frenchman. No known cause of thrombosis was found but spontaneous formation of erythroid colonies occurred on bone marrow cultures. This indicated the existence of a latent myeloproliferative disorder, a frequent cause of hepatic vein thrombosis. We suggest that this association of a membranous obstruction of the inferior vena cava with a known, albeit often overlooked, cause of hepatic vein thrombosis provides strong support to the thrombosis theory of membrane formation.
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