• J Bone Joint Surg Br · Jul 1991

    Osteolytic changes accompanying degradation of absorbable fracture fixation implants.

    • O M Böstman.
    • Helsinki University Central Hospital, Finland.
    • J Bone Joint Surg Br. 1991 Jul 1; 73 (4): 679-82.

    AbstractWe analysed the radiographs of 67 patients with displaced malleolar fractures treated by open reduction and internal fixation using absorbable polyglycolide rods. Seventeen patients developed a discharging inflammatory foreign-body reaction, a complication unique to these fixation devices. In 34 patients ovoid osteolytic foci, usually 5 to 10 mm in diameter, appeared within the implant channels six to 12 weeks after the operation. The same lesion occurred in 14 of the 17 patients who developed a foreign-body reaction, whereas only 20 out of the 50 patients with an uneventful course showed osteolytic areas (p less than 0.01). In patients with a foreign-body reaction the osteolytic foci tended to occur in the deepest parts of the implant channels. However, after one year the normal structure of the bone was restored.

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