• Manju Puri, Poonam Taneja, Neha Gami, and Harmeet S Rehan.
• Department of Obstetrics and Gynecology, Lady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital, Delhi, India. purimanju@rediffmail.com
• Int J Gynaecol Obstet. 2012 Sep 1;118(3):210-2.

ObjectiveTo determine the optimal dose of oxytocin to be injected intraumbilically after fetal delivery for active management of the third stage of labor.MethodsA prospective randomized study was carried out with 125 primigravidas to compare the duration of the third stage of labor following the intraumbilical administration of 50 mL of a normal saline solution alone (in a control group), or with 10 IU, 20 IU, or 30 IU of oxytocin. The volumes of blood lost were also compared.ResultsCompared with the control group, the duration of the third stage of labor was significantly reduced in the 3 study groups (P<0.001), and the maximum reduction was in the group that received 30 IU of oxytocin. Blood loss and hematocrit values followed the same pattern.ConclusionAdministering 30 IU of oxytocin intraumbilically in 50 mL of a normal saline solution after fetal delivery is a simple, noninvasive, and effective method for active management of the third stage of labor.Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

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