• Gloria Horta, Sebastián Soto, and Gonzalo Labarca.
• Complejo Asistencial Dr. Víctor Ríos Ruiz, Los Ángeles, Chile.
• Rev Med Chil. 2021 Mar 1; 149 (3): 393-398.

BackgroundInflammatory Bowell Diseases (IBD), either ulcerative colitis (UC) or Chron's disease (CD) are commonly associated with intestinal malabsorption, and insufficient levels 1-25 hydroxycholecalciferol (vitamin D). These insufficient levels could be linked with an increased risk of clinical disease activity.AimTo report vitamin D levels in patients with IBD living in Southern Chile and their possible association with clinical disease activity.Material And MethodsA prospective, observational study in outpatients with IBD living in Los Angeles, Chile. Demographic data and clinical activity using clinical scores were recorded. Vitamin D levels and fecal calprotectin were measured.ResultsWe studied 44 patients, 32 (73%) with UC and 12 (27%) with CD. The median age at diagnosis was 33 years old. Forty-one (93%) had mild-inactive disease and 3 (7%) a moderate disease. Mean vitamin D levels were 15.2 ± 7.1 ng/ml. Twenty five percent of patients had sufficient levels (> 20 ng/ml), 35% insufficient levels and 40% poor levels. No association between these levels and disease activity was found.ConclusionsThese patients with IBD had a high frequency of hypovitaminosis D.

14 keywords...

hide…