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Ulus Travma Acil Cer · Sep 2021
Case ReportsContinuous veno-venous hemodiafiltration in metformin-associated lactic acidosis caused by a suicide attempt: A report of two cases.
- Bahattin Tuncali, Ayşe Gül Temizkan Kırkayak, and Pınar Zeyneloğlu.
- Department of Anesthesiology and Reanimation, Başkent University Faculty of Medicine, Ankara-Turkey.
- Ulus Travma Acil Cer. 2021 Sep 1; 27 (5): 595-599.
AbstractLactic acidosis is the most important and life-threatening side effect of metformin that is widely used in the treatment of type 2 diabetes mellitus. In this case report, two cases who were treated in our intensive care unit for lactic acidosis due to high-dose metformin intake for suicidal purposes are presented. The first patient could be successfully treated with continuous venous-venous hemodiafiltration (CVVHDF) and supportive therapy. The second case required endotracheal intubation and mechanical ventilation in addition to CVVHDF and supportive therapy due to delay in treatment.
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