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Oncology nursing forum · Sep 2017
Comparative StudyEthical Considerations in Conducting Pragmatic Trials in Oncology.
- Marilyn J Hammer.
- Mount Sinai Hospital.
- Oncol Nurs Forum. 2017 Sep 1; 44 (5): 537-539.
AbstractPragmatic trials evaluate interventions in real-life scenarios, which differ from explanatory trials that control for numerous factors and variables to best determine causal associations. Each approach has advantages and disadvantages. Conducting pragmatic research trials while maintaining the tenets of the ethical conduct of research can sometimes be challenging, particularly regarding informed consent. In this column, distinctions between pragmatic and explanatory trials are discussed from an ethical view.
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