• Na-Ying Zuo, Yuan-da Zhang, Qing-Wei Dong, Jing Bi, and Xiao Liu.
• Na-ying Zuo, Department of Gastroenterology, Baoding Children's Hospital, Baoding, Hebei, 071000, P.R. China. Key Laborary of Clinical Research on Respiratory Digestive Disease, Hebei Baoding, 071000, China.
• Pak J Med Sci. 2021 Sep 1; 37 (5): 1430-1434.

ObjectivesTo evaluate the outcome of anti-HP treatment on the nutritional status of children with Helicobacter pylori-positive gastritis.MethodsSixty children with Helicobacter pylori-positive gastritis admitted to our hospital from June 2018 to June 2020 were selected as the experimental group, and 60 healthy normal people (Hp negative) were selected as the control group. The experimental group were given anti-HP treatment, and the improvement of their clinical symptoms after treatment and the changes of nutritional indexes such as hemoglobin and serum ferritin were observed one year after treatment. Gastroscopy was performed before treatment and four weeks after treatment, and the improvement of gastric inflammation and the positive rate of Hp were compared and analyzed before and after treatment.ResultsThe nutritional indicators of the children in experimental group were inferior compared with those in the control group (p<0.05). The clinical symptoms and signs of the experimental group were significantly alleviated after anti-Hp treatment, and the biochemical indicators were significantly improved after one Year of follow-up compared with those before treatment (p<0.05). The incidence of moderate and severe gastric mucosal inflammation in the experimental group decreased from 70% before treatment to 17% (p<0.05). The HP infection decreased from 100% before treatment to 13% (p<0.05).ConclusionHelicobacter pylori infection has a negative impact on the nutritional status of children. Anti-HP therapy can improve the gastrointestinal symptoms and nutritional status of children, which plays an important role in the growth and development of children.Copyright: © Pakistan Journal of Medical Sciences.

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