• Ryotaro Otsuka, Toshiyuki Takahashi, Tomoo Inoue, Wakiko Saruta, Hiroya Shimauchi, Ryo Kanematsu, Manabu Minami, and Junya Hanakita.
• Spinal Disorders Center, Fujieda Heisei Memorial Hospital, Fujieda, Japan. Electronic address: ryotaro1990.711@gmail.com.
• World Neurosurg. 2021 Nov 1; 155: e646-e654.

BackgroundThe prevalence of osteoporotic vertebral compression fracture (OVCF) is increasing. The indications for and efficacy of balloon kyphoplasty (BKP) are controversial. We sought to identify predictors of outcome after BKP in patients with OVCF.MethodsBetween January 2001 and December 2019, 152 patients underwent BKP for painful OVCFs at our institution. This study included 115 patients who were followed for >12 months, and their data were retrospectively analyzed. With regard to the degree of independent living 1 year after BKP, patients were divided into a good outcome group (composed of patients who could independently go indoors) and a poor outcome group. We analyzed factors associated with outcome and subsequent OVCF.ResultsMean age of patients was 77.9 years, 58.2% were female, 81% had a good outcome, and 19% had a poor outcome. Univariable analysis revealed significant differences in age, bone mineral density, preoperative vertebral body decompression rate, body mass index (BMI), preoperative Japanese Orthopaedic Association score, preoperative modified Rankin Scale score, and subsequent OVCF. Multivariable logistic analysis showed that low BMI (odds ratio 1.415, 95% confidence interval 1.06-1.87, P = 0.046) and subsequent OVCF (odds ratio 0.13, 95% confidence interval 0.02-0.69, P = 0.044) were independent risk factors. The incidence of subsequent OVCF was also lower among patients with higher BMI (odds ratio 0.83, 95% confidence interval 0.72-0.95, P = 0.001).ConclusionsBMI and subsequent OVCF are the most influential predictors of independent living 1 year after BKP for OVCF.Copyright © 2021 Elsevier Inc. All rights reserved.

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