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- Taiki Okumura, Kenta Mitsui, Seiichi Daikuhara, Toshiharu Tatai, Hiroko Itagaki, Hideharu Miyabayashi, and Yukio Gibo.
- Department of Gastroenterology, National Hospital Organization Matsumoto Medical Center, Japan.
- Intern. Med. 2022 Mar 1; 61 (5): 657-662.
AbstractDisseminated carcinomatosis of the bone marrow (DCBM) is often accompanied by disseminated intravascular coagulation (DIC) and has a poor prognosis. DCBM develops most frequently in gastric cancer and is rarely associated with intrahepatic cholangiocarcinoma. A 41-year-old man was incidentally found to have DIC on his regular visit for ulcerative colitis and was diagnosed with DCBM with intrahepatic cholangiocarcinoma. He received intensive care, including chemotherapy, but died suddenly from hyperkalemia, possibly due to tumor lysis syndrome (TLS). The autopsy showed the periductal infiltrating type of intrahepatic cholangiocarcinoma and tumor necrosis, possibly due to chemotherapy, indicating the effectiveness of chemotherapy for DCBM with intrahepatic cholangiocarcinoma.
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