• Internal medicine · Mar 2022

    Case Reports

    A Case of Massive Polycystic Liver with a Poor Performance Status Successfully Treated by ABO-incompatible Adult Living-donor Liver Transplantation while Overcoming Complications.

    • Satoshi Takakusagi, Yuichi Masuda, Hitoshi Takagi, Yozo Yokoyama, Kazuko Kizawa, Kyoko Marubashi, Takashi Kosone, and Yuji Soejima.
    • Department of Gastroenterology and Hepatology, Kusunoki Hospital, Japan.
    • Intern. Med. 2022 Mar 15; 61 (6): 841-849.

    AbstractWe encountered a 47-year-old woman with polycystic liver disease (PLD) and severe malnutrition successfully treated by living-donor liver transplantation (LDLT). Her PLD became symptomatic with abdominal distension and appetite loss. Transcatheter arterial embolization and percutaneous cyst drainage failed to improve her symptoms. ABO-incompatible LDLT from her husband was performed after rituximab administration and mycophenolate mofetil introduction. Although she showed severe postoperative complications, she ultimately regained the ability to walk and was discharged. Because advanced PLD cases are difficult to treat conservatively or with surgery, like fenestration and hepatectomy, liver transplantation should be considered before it becomes too late.

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