• J. Cardiothorac. Vasc. Anesth. · Feb 2022

    Prevalence, Characteristics and Preoperative Predictors of Chronic Pain After Double-Lung Transplantation: A Prospective Cohort Study.

    • Quentin Laurent, Mireille Michel-Cherqui, Barbara Szekely, Matthieu Glorion, Edouard Sage, Julie Trichereau, Marc Fischler, Julien Fessler, and GuenMorgan LeMLDepartment of Anesthesiology and Pain Management Clinic, Hôpital Foch, 92150 Suresnes, France, and Université Versailles-Saint-Quentin-en-Yvelines, Versailles, France..
    • Department of Anesthesiology and Pain Management Clinic, Hôpital Foch, 92150 Suresnes, France, and Université Versailles-Saint-Quentin-en-Yvelines, Versailles, France.
    • J. Cardiothorac. Vasc. Anesth. 2022 Feb 1; 36 (2): 500-509.

    ObjectiveData on chronic pain after lung transplantation are heterogeneous. This study prospectively explored the prevalence, characteristics, consequences, and preoperative predictors of pain in lung transplant recipients.DesignA prospective cohort study.SettingThe Foch University Hospital, Suresnes, France.ParticipantsPatients registered on the waiting list for double-lung transplantation in the authors' institution from August 2008 to October 2013 and transplanted.InterventionsDatabase prospectively completed in real time during consultations with a pain-certified anesthesiologist before lung transplantation and six months after surgery.Measurements And Main ResultsThe assessments explored pain in three components: physical (intensity, location, neuropathic and sensory qualifications, treatments), mental (anxiety and depression), and quality of life. Seventy-two patients underwent all assessments. The prevalence of six-month postoperative pain was 68.0%. Among patients with pain, 83.3% reported mild average pain and 26.5% had neuropathic pain. All patients who responded to the questionnaire took analgesics frequently, but only 9.1% took opioids. Patients with pain reported higher levels of anxiety (p = 0.02) and depression (p = 0.01). Additionally, they presented with increased difficulty in ambulation (p = 0.03), work (p = 0.02), and sleep (p = 0.02). The maximum level of preoperative pain was an independent risk factor of six-month postoperative pain (p = 0.03).ConclusionsThe authors report a high prevalence of chronic pain with concomitant psychosocial repercussions despite a reported mild intensity. Perioperative measures, such as personalized and detailed management plans, could improve patient satisfaction.Copyright © 2021 Elsevier Inc. All rights reserved.

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