• Int. J. Clin. Pract. · Nov 2021

    Characteristics of Hospitalized COVID-19 Patients and Parameters Associated with Severe Pneumonia.

    • Onur Turan, Arzu Mirici, Serap Duru Akçalı, Pakize Ayşe Turan, Özgür Batum, Aysun Şengül, Ekici ÜnsalZühalZChest Diseases Department, Başkent University Adana Dr. Turgut Noyan Application and Research Center, Adana, Turkey., Işık KabakoğluNalanNChest Diseases Department, İzmir Bornova Dr. Türkan Özilhan State Hospital, İzmir, Turkey., Nalan Ogan, Şerife Torun, Güntülü Ak, Şule Akçay, Berna Kömürcüoğlu, Nazan Şen, Pınar Mutlu, and Ülkü Yilmaz.
    • Chest Diseases Department, Izmir Katip Celebi University Atatürk Research and Training Hospital, İzmir, Turkey.
    • Int. J. Clin. Pract. 2021 Nov 1; 75 (11): e14786.

    BackgroundAfter the first case of coronavirus disease 2019 (COVID-19) was reported in China in December 2019, it caused a global pandemic, including Turkey.ObjectivesThe aim of this study was to analyse the characteristics of hospitalised COVID-19 patients and assess the parameters related to severe pneumonia.MethodsIncluded in the study were hospitalised COVID-19 patients with positive naso-oropharyngeal swabs. Patients' demographics, admission symptoms, laboratory and radiological findings were recorded retrospectively.ResultsOf 1013 patients, 583 were males (57.6%) and 430 were females (42.4%), with a mean age of 53.7 ± 17.9. More than half of the patients had at least one comorbidities, the most common of which were hypertension and diabetes mellitus. Cough (59.8%), fatigue (49.5%) and fever (41.2%) were the most common presenting symptoms. Of the hospitalised COVID-19 patients, 84.9% had pneumonia and 83.5% had typical radiological COVID-19 appearances (94.5%: ground-glass areas). The most common laboratory findings were high C-reactive protein (CRP) (73.6%) and lactate dehydrogenase (LDH) (46.2%) levels, as well as lymphopenia (30.1%). Severe pneumonia was present in 28.1% of COVID-19 patients. Multivariate logistic regression analysis indicated that advanced age, hypotension, anaemia and elevated CRP and LDH serum levels were independent risk factors for the severity of COVID-19 pneumonia (P = .011, .006, .017, .003 and .001, respectively).ConclusionThis study, as one of the first multicentre studies about characteristics of COVID-19 in Turkey, may guide about disease-related parameters and severity of pneumonia. Age, blood pressure, complete blood count and routine biochemical tests (including CRP and LDH) would appear to be important parameters for the evaluation of the severity of COVID-19 pneumonia.© 2021 John Wiley & Sons Ltd.

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