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Case Reports
Successful treatment of relapsing autoimmune thrombotic thrombocytopenic purpura with rituximab.
- Senthilkumar Sankararaman, Majed Jeroudi, and Hassan Ibrahim.
- Department of Pediatrics, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
- Pediatr Int. 2014 Dec 1; 56 (6): 914-918.
AbstractThrombotic thrombocytopenic purpura (TTP) is a rare but life-threatening condition characterized by thrombotic microangiopathy. The standard treatment for TTP is plasmapheresis. For refractory or relapsing cases, various immunosuppressive agents have been tried, and among them rituximab has shown promising results. TTP is rarer in the pediatric age group and the use of rituximab in children with TTP is limited. Reported herein is the successful treatment of relapsing autoimmune TTP with rituximab in a 12-year-old girl. © 2014 Japan Pediatric Society.
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