• Cochrane Db Syst Rev · Jan 2001

    Review

    Oral steroids for bronchiectasis (stable and acute exacerbations).

    • T Lasserson, K Holt, and M Greenstone.
    • Public Health Sciences, St George's Hospital Medical School, Cranmer Terrace, Tooting, London, UK, SW17 0RE. tlassers@sghms.ac.uk
    • Cochrane Db Syst Rev. 2001 Jan 1 (4): CD002162.

    BackgroundInflammation plays a significant role in the pathophysiology of bronchiectasis. Two small studies have shown small benefits from inhaled corticosteroids and oral corticosteroids may be of benefit in bronchiectasisObjectivesTo determine the efficacy of oral corticosteroids in acute and stable bronchiectasisSearch StrategyThe Cochrane Airways Group clinical trials register, derived from MEDLINE, EMBASE and hand searching of major journals, was searched using the terms bronchiectasis AND corticosteroid* OR (beclomethasone, cortisone, deflazacort, hydrocortisone, methylprednisolone, prednisolone, dexamethasone and triamcinoloneSelection CriteriaOnly randomised controlled trials were consideredData Collection And AnalysisNo trials met the inclusion criteria for the reviewMain ResultsNo randomised controlled trials were identifiedReviewer's ConclusionsThere are no randomised trials upon which to make recommendations about the use of oral corticosteroids in acute or stable bronchiectasis.

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