• Rev Assoc Med Bras (1992) · Apr 2021

    Ankle-brachial index and subclinical atherosclerosis in type 1 diabetes.

    • Alexandra Corrêa Gervazoni Balbuena de Lima, Mariana Fiuza Gonçalves, Ester Vasconcelos Rocha, Luciana Bartolmei Orru D'Ávila, and André Neves Mascarenhas.
    • Hospital Regional da Asa Norte, Secretaria de Saúde do Distrito Federal - Brasília, (DF), Brazil.
    • Rev Assoc Med Bras (1992). 2021 Apr 1; 67 (4): 505-510.

    ObjectiveTo assess the prevalence of altered ankle-brachial index (<0.9 or >1.3) in patients with type 1 diabetes and to compare it with the presence of subclinical atherosclerosis by carotid ultrasound.MethodsProspective, cross-sectional study in which 45 adults with type 1 diabetes were evaluated (age 34±10 years, 46.7% men). The data collected included anamnesis, clinical evaluation, calculation of the ankle-brachial index (relationship between systolic blood pressure in the ankle and brachial artery), and performance of carotid ultrasound.ResultsThirty-two patients had ankle-brachial index >1.3 (66.7%) and no patient had ankle-brachial index <0.9. Carotid echocardiography was performed on 21 patients, 4 (19%) of whom had atherosclerosis. Age >35 years and ankle-brachial index >1.4 showed a good correlation with atherosclerosis (r=0.49, p=0.021; r=0.56, p=0.008, respectively). A model associating age >35 years and ankle-brachial index >1.4 showed an excellent relationship with atherosclerosis (r=0.59, p=0.004).ConclusionsOur study showed that vascular calcification (ankle-brachial index >1.4) was frequent in this population with type 1 diabetes and associated with subclinical atherosclerosis. A model combining ankle-brachial index >1.4 and age >35 years showed an excellent correlation with atherosclerosis and can assist in clinical suspicion and optimize the request for additional tests.

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