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JNMA J Nepal Med Assoc · Nov 2020
Case ReportsRecurrent Positivity of SARS-CoV-2 RNA in a Clinically Recovered COVID-19 Patient with End Stage Renal Disease: A Case Report.
- Richa Nepal, Kalyan Sapkota, Santosh Gurung, Pramod Paudel, Prateek Neupane, and Kamlesh Kumar Sah.
- Department of Internal Medicine, Bharatpur Hospital, Bharatpur, Province-3, Chitwan, Nepal.
- JNMA J Nepal Med Assoc. 2020 Nov 22; 58 (231): 918922918-922.
AbstractRecurrent or persistent positivity of SARS-CoV-2 RNA in clinically recovered COVID-19 patients have been reported worldwide. However, replication competent live viruses were not recovered beyond two to three weeks from onset of symptoms in mild to severe cases of COVID-19. End stage renal disease is characterized by uremia induced immune dysfunction that increases the risk of infectious diseases including COVID-19. The clinical implications of recurrent or persistently positive SARS-CoV-2 RNA in immunocompromised patients are difficult to be generalized to findings as in immunocompetent patients. We report a case of end stage renal disease with recent history of recovered COVID-19 pneumonia, who again presented with positive reverse transcriptase- polymerase chain reaction (RT-PCR) test for SARS-CoV-2 RNA.
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