• Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi · Nov 2012

    Review

    [Progress of in vivo study on degradable magnesium alloys application as bone-implant materials].

    • Zhengrong Qi, Qiang Zhang, Yi Yin, and Yan Wang.
    • Department of Orthopaedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China.
    • Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2012 Nov 1; 26 (11): 1381-6.

    ObjectiveTo review the progress of in vivo study on degradable magnesium alloys application as bone-implant materials.MethodsRecent literature was extensively reviewed and summarized, concerning the in vivo study on degradable magnesium alloys as orthopaedic implants.ResultsMagnesium alloys possess a natural ability to degrade via corrosion in vivo, which is promising candidate material for orthopaedic medical device applications. A great progress has been made to improve in vivo performance and integration with bone tissue. However, the degradation mechanism of magnesium-based materials in the physiological environment and long-term effect on body are not available. The modulation of the corrosion rate of magnesium alloys must also be accomplished.ConclusionMagnesium alloys have the potential to serve as degradable implants for orthopaedic applications, but a great deal of further investigation is still necessary.

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