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J. Clin. Microbiol. · Jan 2010
Comparative StudyComparison of a rapid antigen test with nucleic acid testing during cocirculation of pandemic influenza A/H1N1 2009 and seasonal influenza A/H3N2.
- Jen Kok, Christopher C Blyth, Hong Foo, Jason Patterson, Janette Taylor, Kenneth McPhie, V Mala Ratnamohan, Jonathan R Iredell, and Dominic E Dwyer.
- Centre for Infectious Diseases and Microbiology Laboratory Services, Level 3, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales 2145, Australia. jen.kok@swahs.health.nsw.gov.au
- J. Clin. Microbiol. 2010 Jan 1; 48 (1): 290-1.
AbstractThe rapid diagnosis of influenza is critical in optimizing clinical management. Rapid antigen tests have decreased sensitivity in detecting pandemic influenza A/H1N1 2009 virus compared to seasonal influenza A subtypes (53.4% versus 74.2%, P < 0.001). Nucleic acid tests should be used to detect pandemic influenza virus when rapid antigen tests are negative.
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