• Clin Chem Lab Med · Jun 2020

    Review

    COVID-19: progression of disease and intravascular coagulation - present status and future perspectives.

    • Job Harenberg and Emmanuel Favaloro.
    • University of Heidelberg, DOASENSE GmbH, Waldhofer Str. 102, 69123 Heidelberg, Germany.
    • Clin Chem Lab Med. 2020 Jun 25; 58 (7): 1029-1036.

    AbstractThe timely and accurate diagnosis of infection with severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), remains the cornerstone of efforts to provide appropriated treatment for patients, to limit further spread of the virus and ultimately to eliminate the virus from the human society. We focus this article on (a) developments for improvement of diagnosis of specific SARS-CoV-2 virus, (b) laboratory changes in the immunologic and coagulation system, (c) therapeutic options for anticoagulant treatment of seriously affected patients and (d) on the perspectives through improvement of diagnostic and therapeutic medical procedures.

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