• Pediatric neurology · Jul 2014

    Case Reports

    Use of ketamine in a newborn with refractory status epilepticus: a case report.

    • Anna Tarocco, Elisa Ballardini, and Giampaolo Garani.
    • Department of Medical Sciences, Pediatric Section, S. Anna University Hospital, Ferrara, Italy.
    • Pediatr. Neurol. 2014 Jul 1; 51 (1): 154-6.

    BackgroundBrain malformations represent a major cause of refractory seizures. Standardized protocols to treat status epilepticus of newborn are not available in the literature.PatientWe present a case report of use of ketamine administered to a late preterm with Pierre Robin sequence, lissencephaly, polymicrogyria, and severe epilepsy.ResultsThe infusion of ketamine permitted resolution of status epilepticus, cardiorespiratory stabilization, and improved parental care for 15 days. No significant side effects were noted.ConclusionIn the literature there are few studies regarding the use of ketamine for refractory status epilepticus, and only in nine of these described the use of, ketamine in children (2 months-18 years). This is the first report to document the effective use of ketamine in the newborn with status epilepticus.Copyright © 2014 Elsevier Inc. All rights reserved.

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