• Clin Med (Lond) · Sep 2021

    Case Reports

    Lessons of the month 1: Longitudinal extensive transverse myelitis following AstraZeneca COVID-19 vaccination.

    • Alp Aa Notghi, Joseph Atley, and Mark Silva.
    • Gloucester Royal Hospital, Gloucester, UK a.notghi@nhs.net.
    • Clin Med (Lond). 2021 Sep 1; 21 (5): e535e538e535-e538.

    AbstractLongitudinal extensive transverse myelitis (LETM) is a rare but recognised complication of vaccination. We report the case of a 58-year-old man admitted to hospital 10 days after his first AstraZeneca COVID-19 vaccination with progressive neurological symptoms and signs, and investigations and imaging consistent with LETM.This case reviews the literature and the investigative process behind excluding other diagnoses given the patient's background of pulmonary sarcoidosis. It is unique in being the first UK report of a case of LETM with a strong temporal link to COVID-19 vaccination.© Royal College of Physicians 2021. All rights reserved.

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