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Regional-Anaesthesie · Oct 1986
Comparative Study Clinical Trial Controlled Clinical Trial[Peridural anesthesia with bupivacaine-CO2 and bupivacaine-HCl. A comparative study].
- M A Mattila, T Tuppurainen, H M Larni, A Gordin, and H Salo.
- Reg Anaesth. 1986 Oct 1; 9 (4): 105-9.
AbstractCarbonated bupivacaine and bupivacaine hydrochloride were used for epidural anaesthesia in patients undergoing surgery of the lower extremities. Thirty patients received 20 ml 0.5% bupivacaine hydrochloride and 32 patients 20 ml 0.42% carbonated bupivacaine. Carbonated bupivacaine had a more rapid onset of action and spread of both sensory and motor blockade than its hydrochloride salt. The differences were statistically significant.
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