• Ir J Med Sci · Aug 2022

    Can we trust in Sars-CoV-2 rapid antigen testing? Preliminary results from a paediatric cohort in the emergency department.

    • Marco Denina, Virginia Giannone, Antonio Curtoni, Elisa Zanotto, Silvia Garazzino, Antonio Francesco Urbino, and Claudia Bondone.
    • Department of Pediatric Emergency, Regina Margherita Children's Hospital, Turin, Italy. marco.denina@gmail.com.
    • Ir J Med Sci. 2022 Aug 1; 191 (4): 1767-1770.

    BackgroundRapid identification of Covid-19 in the paediatric emergency department is critical; Antigen tests are fast but poorly investigated in children.AimsTo investigate Sars-CoV-2 antigen rapid test in children.MethodsWe compare the performance of LumiraDx with molecular tests in a paediatric emergency department.ResultsA retrospective cohort of 191 patients with AT and PCR tests performed in the same episode was analysed; 16% resulted positive for Sars-CoV-2. Using the PCR test as the gold standard, we calculated antigen testing overall sensitivity of 94.1%, specificity of 91.9%, and NPV of 99.4%. Only one false-negative test was found.ConclusionsAT may be helpful in the initial screening of patients at PED.© 2021. Royal Academy of Medicine in Ireland.

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