• Lok Bahadur Shrestha, Gopiram Syangtan, Ajaya Basnet, Krishna Prasad Acharya, Arun Bahadur Chand, and Khilasa Pokhrel.
• School of Medical Sciences and The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia.
• JNMA J Nepal Med Assoc. 2021 May 25; 59 (237): 518-522.

AbstractStaphylococcus aureus is both a frequent commensal and a leading cause of endocarditis, bacteremia, osteomyelitis and skin and soft tissue infections and device-related infections. We performed this minireview to summarize the prevalence of Staphylococcus aureus among clinical samples and estimate the proportion of methicillin-resistant Staphylococcus aureus. The prevalence of Staphylococcus aureus among clinical isolates in Nepal is 34.5%. On average, the proportion of multi-drug resistance in Staphylococcus aureus is 57.1%. Methicillin-resistant Staphylococcus aureus accounts for a total of 41.7%. Inducible clindamycin resistance was detected in about 35% of the isolates. A regular antimicrobial resistance surveillance mechanism is necessary to mitigate the development of resistance among organisms and further spread of superbugs like methicillin-resistance Staphylococcus aureus.

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