• Samikshya Kandel, Sundar Khadka, Mahesh Lamsal, Bimlesh Jha, Sunil Paudyal, Swotantra Gautam, Sagar Poudel, Mukunda Sharma, and Jeena Amatya.
• Nepal Academy of Science and Technology, Khumaltar, Lalitpur.
• JNMA J Nepal Med Assoc. 2021 May 25; 59 (237): 486-489.

IntroductionHuman Immunodeficiency Virus is a lentivirus that causes human immunodeficiency virus infection and over time, acquired immunodeficiency syndrome. Cluster of Differentiation 4+ T cell count of people living with this infection play a vital role to determine infection progression and necessary treatment changes. This study was conducted to find out the prevalence of low Cluster of Differentiation 4+ T Cell Count in the People Living with human immunodeficiency virus/ acquired immunodeficiency syndrome.MethodsA descriptive cross-sectional study was conducted between June to August 2018 in the Human Immunodeficiency virus and Hepatitis Reference Unit of National Public Health Laboratory, Ministry of Health and Population Teku. Ethical approval was taken (Reference Number 2912) and a total of 550 seropositive cases of Human Immunodeficiency Virus-1 undergoing antiretroviral therapy were studied. Convenient sampling technique was used. Data was analysed by Statistical Package for the Social Sciences.ResultsSeventeen (3.1%) of patients had Cluster of Differentiation 4+ T cell counts below 100 cells/mm3 of blood. The mean Cluster of Differentiation 4+ T cell count was 509.3 cells/mm3 of blood. Of the total samples, 280 (50.9%) were males, 268 (48.7%) were females, and the rest 2 (0.4%) were of other gender.ConclusionsMajority of people living with human immunodeficiency virus/ acquired immunodeficiency syndrome were found immune-competent.

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