• Birendra Bhagat, Bijaya Chandra Aacharya, Sarita Gurung, BhattaRanjan RajRRDepartment of Pathology, B. P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal., and Aasiya Rajbhandari.
• Department of Gynecological Oncology, National Academy of Medical Sciences, Kathmandu, Nepal.
• JNMA J Nepal Med Assoc. 2021 Aug 12; 59 (240): 814-817.

AbstractCervical carcinoma is the most common cause of mortality due to cancer in Nepal. Carcinosarcoma is a very rare subtype of cervical cancer which is characterized by the presence of both epithelial and mesenchymal malignant component. It constitutes less than 1% of cervical carcinoma. Due to the low occurrence of the disease, most of the data on treatment and prognosis are based on case reports and series. Here, we report a case of 69 years, female with cervical cancer (FIGO IIA2). Histopathological and immunohistochemical analysis of cervical biopsy initially showed primary adenosarcoma of the cervix. The tumor was non-responsive to primary treatment with concurrent chemoradiation. Later she was treated with abdominal hysterectomy and bilateral salpingo-oophorectomy. The final histopathology of the resected specimen showed a sarcomatous component along with carcinomatous changes in the endocervical glands favouring the diagnosis of carcinosarcoma of the cervix.

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