• JNMA J Nepal Med Assoc · Apr 2021

    Review

    Management of Locally Advanced Esophageal Cancer.

    • Binay Thakur, Mukti Devkota, and Manish Chaudhary.
    • Department of Surgical Oncology, BP Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal.
    • JNMA J Nepal Med Assoc. 2021 Apr 30; 59 (236): 409-416.

    AbstractEsophageal cancer is diagnosed usually at a locally advanced stage. Surgery alone has less optimal results and a multimodality approach has been established as the standard of care for cII-III stages of esophageal cancer. This review focuses on the recent evidences of management of esophageal cancer with various variations in approaches in Eastern and Western countries. The major difference is the selection of induction treatment. Till the results of some ongoing trials become available, most of the evidences support neoadjuvant chemoradiation followed by surgery for squamous cell carcinoma and perioperative chemotherapy and surgery for adenocarcinoma.

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