• Shahnaz Sultan, Madelin R Siedler, Rebecca L Morgan, Toju Ogunremi, Philipp Dahm, Lisa A Fatheree, GetchiusThomas S DTSDGuideline Strategy and Operations, American Heart Association and American College of Cardiology, Dallas, TX, USA., Pamela K Ginex, Priya Jakhmola, Emma McFarlane, M Hassan Murad, Robyn L Temple Smolkin, Yasser S Amer, Murad Alam, Bianca Y Kang, Yngve Falck-Ytter, and Reem A Mustafa.
• Division of Gastroenterology, Hepatology, and Nutrition, University of Minnesota, Minneapolis VA Health Care System, Minneapolis, MN, USA. ssultan@umn.edu.
• J Gen Intern Med. 2022 Aug 1; 37 (11): 266926772669-2677.

BackgroundThe development of rigorous, high-quality clinical guidelines increases the need for resources and skilled personnel within guideline-producing organizations. While collaboration between organizations provides a unique opportunity to pool resources and save time and effort, the collaboration presents its own unique challenges.ObjectiveTo assess the perceived needs and current challenges of guideline producers worldwide related to guideline development and collaboration efforts.DesignSurvey questions were developed by the Guidelines International Network and the US GRADE Network, pilot-tested among attendees of a guideline development workshop, and disseminated electronically using convenience and snowball sampling methods.ParticipantsA total of 171 respondents representing 30 countries and more than 112 unique organizations were included in this analysis.Main MeasuresThe survey included free-response, multiple-choice, and seven-point Likert-scale questions. Questions assessed respondents' perceived value of guidelines, resource availability and needs, guideline development processes, and collaboration efforts of their organization.Key ResultsTime required to develop high-quality systematic reviews and guidelines was the most relevant need (median=7; IQR=5.5-7). In-house resources to conduct literature searches (median=4; IQR=3-6) and the resources to develop rigorous guidelines rapidly (median=4; IQR=2-5) were perceived as the least available resources. Difficulties reconciling differences in guideline methodology (median=6; IQR=4-7) and the time required to establish collaborative agreements (median=6; IQR=5-6) were the most relevant barriers to collaboration between organizations. Results also indicated a general need for improvement in conflict of interest (COI) disclosure policies.ConclusionThe survey identified organizational challenges in supporting rigorous guideline development, including the time, resources, and personnel required. Connecting guideline developers to existing databases of high-quality systematic reviews and the use of freely available online platforms may facilitate guideline development. Guideline-producing organizations may also consider allocating resources to hiring or training personnel with expertise in systematic review methodologies or utilizing resources more effectively by establishing collaborations with other organizations.© 2021. This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.

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