• Dtsch. Med. Wochenschr. · Oct 2021

    [Advances in Lung Cancer Treatment].

    • Christian Schulz.
    • Klinik und Poliklinik für Innere Medizin II, Bereich Pneumologie, Klinikum der Universität Regensburg.
    • Dtsch. Med. Wochenschr. 2021 Oct 1; 146 (19): 1283-1286.

    Immuno Oncologic Monotherapy For Nsclc5-year survival data from the KEYNOTE-024 trial confirm the sustained efficacy of immuno-oncologic monotherapy in patients with NSCLC with high PD-L1 expression (≥ 50 %). DUAL IMMUNOTHERAPY IN COMBINATION WITH CHEMOTHERAPY AS FIRST-LINE THERAPY FOR NSCLC:  Nivolumab plus impilimumab in combination with 2 cycles of platinum-containing chemotherapy improves survival in NSCLC patients.Novel Targets And Treatment OptionsEntrectinib and larotrectinib with efficacy in NTRK fusion-positive NSCLC. Selpercatinib and pralsetinib with efficacy in RET fusion-positive NSCLC. Mobocertinib with efficacy in EGFRex20ins mutation of the EGFR gene. Sotorasib with efficacy in kRAS-G12C mutation of NSCLC.National Network Genomic Medicine Lung Cancer (Nngm)The nationwide network nNGM provides NSCLC patients with access to state-of-the-art molecular diagnostics and the latest treatment options.Thieme. All rights reserved.

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