• Der Internist · Dec 2021

    Review Case Reports

    [Severe secondary sclerosing cholangitis as manifestation of a very rare underlying disease].

    • Britta Franziska Zecher, Roman Zenouzi, Melanie Lang, Panagiotis Karagiannis, Till Clauditz, Lutz Fischer, Martina Sterneck, Christoph Schramm, Ansgar W Lohse, and Marcial Sebode.
    • I. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
    • Internist (Berl). 2021 Dec 1; 62 (12): 1349-1353.

    AbstractLangerhans cell histiocytosis (LCH) is a very rare cause of secondary sclerosing cholangitis. We report the case of a 42-year-old male patient with sclerosing cholangitis and histological evidence of LCH from a bile duct biopsy. Due to rapid disease progression and exhaustion of conservative therapeutic approaches the patient received a liver transplantation. Nearly 2 years after transplantation the patient has a good graft function and no signs of recurrence of the underlying LCH.© 2021. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

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