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- Hannah Bromberg, Young Chang, Diane Portman, and David Craig.
- Department of Supportive Care and H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
- J Palliat Med. 2022 Feb 1; 25 (2): 335-336.
AbstractSelective pan fibroblast growth factor receptor (FGFR) inhibitors have been linked to severe onycholysis, the uncomfortable separation of the nail plate from the nail bed. Recommendations to assist with FGFR inhibitor onycholysis vary based on the severity. We hypothesized that the application of topical lidocaine to mimic a digital nerve block would be beneficial in addition to traditional supportive care interventions and subsequently report its immediate and continued efficacy for targeted therapy-induced onycholysis.
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