• Joost F Ter Woorst, Jules R Olsthoorn, Saskia Houterman, Bart H M van Straten, and Mohamed A Soliman-Hamad.
• Department of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, the Netherlands.
• J. Cardiothorac. Vasc. Anesth. 2022 May 1; 36 (5): 1288-1295.

ObjectivesWomen undergoing coronary artery bypass grafting (CABG) demonstrate higher rates of postoperative morbidity and mortality than men. The aim of this study was to compare the patient profile and long-term outcomes of men and women undergoing isolated CABG.DesignA retrospective patient record study and propensity score-matched analysis.SettingThis single-center study was performed at Catharina Hospital in Eindhoven, The Netherlands.ParticipantsThe study comprised 17,483 patients, of whom 13,564 (77.6%) were men and 3,919 (22.4%) were women.InterventionsCoronary artery bypass grafting was performed between January 1998 and December 2015.Measurements And Main ResultsThe mean follow-up period was 8.8 ± 5.0 years. Women were older than men (67.7 ± 9.4 years v 63.9 ± 9.6 years, p < 0.001) and had lower preoperative hemoglobin levels. Early mortality (30-day) (2.8% v 1.9%; p < 0.001) and one-year mortality (5.2% v 3.8%; p < 0.001) rates were significantly higher in women than in men. Women demonstrated worse long-term survival than men only in the population younger than 70 years. After propensity score matching, female sex was not identified as an independent risk factor for long-term survival.ConclusionsIn the patient population, propensity score-matched analysis showed that female sex was not an independent risk factor for long-term survival after CABG. Poorer survival in women after CABG only was observed in patients <70 years of age.Copyright © 2021 Elsevier Inc. All rights reserved.

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