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Biol. Blood Marrow Transplant. · Aug 2015
ReviewEmerging Influence of the Intestinal Microbiota during Allogeneic Hematopoietic Cell Transplantation: Control the Gut and the Body Will Follow.
- Melissa D Docampo, Jeffery J Auletta, and Robert R Jenq.
- Department of Immunology, Weill Cornell Graduate School of Medical Sciences, New York, New York. Electronic address: med2013@med.cornell.edu.
- Biol. Blood Marrow Transplant. 2015 Aug 1; 21 (8): 1360-6.
AbstractThe intestinal microbiota has many critical roles in maintaining gastrointestinal epithelial and gastrointestinal systemic immune homeostasis. This review provides insight into how allogeneic hematopoietic cell transplantation (HCT) and its associated complications and supportive care therapies affect the microbiota. Additionally, the review discusses how preservation and restoration of the microbiota might be advantageous in decreasing HCT-related morbidity and mortality. Copyright © 2015 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.
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