• Southern medical journal · Dec 2018

    Case Reports

    Uremic Pericarditis: Distinguishing Features in a Now-Uncommon Clinical Syndrome.

    • Daniel Restrepo, Muthiah Vaduganathan, and Andrew Z Fenves.
    • From the Hospital Medicine Unit and the Core Educator Faculty and Renal Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, the Heart and Vascular Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
    • South. Med. J. 2018 Dec 1; 111 (12): 754-757.

    AbstractWe present the case of a 47-year-old man with a history of diabetes mellitus and diabetic nephropathy who was admitted to our hospital with acute uremic myopericarditis. Echocardiography demonstrated a fibrinous pericardial effusion. The patient was initiated on hemodialysis for hyperkalemia, metabolic acidosis, and uremia. He subsequently developed shock from cardiac tamponade, which required emergent pericardiocentesis. He was notably without tachycardia while he was hypotensive, and his admission electrocardiogram did not show typical ST- or PR-segment changes typically associated with acute pericarditis. This case highlights important differences between uremic pericarditis and other prevalent types of acute pericarditis, including the lack of tachycardia during tamponade and normal electrocardiography. Uremic pericarditis is now a less common diagnosis. It is often seen in the setting of previously undiagnosed advanced kidney disease or when patients are ineffectively dialyzed. Given its atypical features, low incidence, and adverse attendant complications, internists must maintain a high degree of suspicion to correctly diagnose acute uremic pericarditis.

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