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- Hiroaki Kitamura, Yasushi Kubota, Rika Tomimasu, Michiaki Akashi, Tadashi Mori, Yutaro Mine, Jun Ando, Somay Yamagata Murayama, Shinya Kimura, and Masaharu Miyahara.
- Department of Internal Medicine, Karatsu Red Cross Hospital, Japan.
- Intern. Med. 2022 Apr 15; 61 (8): 127912831279-1283.
AbstractSarocladium kiliense is ubiquitous in the human environment and is an emerging opportunistic pathogen, especially among immunocompromised hosts. A 77-year-old man diagnosed with aplastic anemia suffered from non-valvular endocarditis. After he passed away, fungal hyphae were observed in several lesions on a postmortem examination. Polymerase chain reaction (PCR) and a DNA sequence analysis revealed S. kiliense as the causative organism. This is the first case report of non-valvular fungal endocarditis caused by S. kiliense identified by PCR and a DNA sequence analysis in an immunocompromised patient. Although rare, invasive fungal infection caused by S. kiliense should be considered in immunocompromised hosts.
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