• Qiang Nai, Mohammad Ansari, Stella Pak, Yufei Tian, Mohammed Amzad-Hossain, Yanhong Zhang, Yali Lou, Shuvendu Sen, and Mohammed Islam.
• Department of Medicine, University of Toledo Medical Center, Toledo, OH 43614, USA.
• J Clin Med Res. 2018 Apr 1; 10 (4): 351-357.

AbstractThyroid storm is a potentially fatal manifestation of thyrotoxicosis. Cardiopulmonary failure is the most common cause of death in thyroid storm. Clinicians should keep in mind that thyroid storm complicated with cardiopulmonary failure can be the first presentation of thyrotoxicosis. As early intervention is associated with improved patient outcome, prompt diagnosis based on clinical grounds is of paramount importance in the management of thyrotoxicosis. A high index of suspicion and the ability of early recognition of impending thyroid storm depends on a thorough knowledge of both the typical and atypical clinical features of this illness. Herein, we report a case of thyroid storm presenting as cardiopulmonary failure in a 51-year-old woman with undiagnosed Grave's disease. Additionally, we review the pathophysiology of cardiopulmonary failure associated with thyrotoxicosis and various treatment modalities for thyroid storm.

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