• Clin J Oncol Nurs · Aug 2017

    Ipilimumab-Based
 Therapy: Consensus Statement From the Faculty of the Melanoma Nursing Initiative on Managing Adverse Events With Ipilimumab Monotherapy and Combination Therapy With Nivolumab.

    • Kathleen M Madden and Brianna Hoffner.
    • New York University Langone Medical Center.
    • Clin J Oncol Nurs. 2017 Aug 1; 21 (4 Suppl): 30-41.

    BackgroundIpilimumab (Yervoy®) therapy improves outcomes in patients with resected stage III melanoma, and ipilimumab alone or combined with nivolumab (Opdivo®) does so in those with unresectable or metastatic melanoma. These immunotherapies are associated with immune-related adverse events (irAEs). With prompt recognition and appropriate management, serious sequelae or unnecessary treatment discontinuation can be prevented.
.ObjectivesThis article presents consensus statements to guide oncology nurses in the recognition and management of irAEs associated with ipilimumab and nivolumab. 
.MethodsMembers of the Melanoma Nursing Initiative reviewed the current literature and clinical experience regarding nursing interventions related to irAEs associated with ipilimumab or ipilimumab and nivolumab therapy.
.FindingsThe care step pathways provided represent a proactive, evidence-based, and comprehensive plan to support optimal patient outcomes.

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