• J Orthop Trauma · Jan 2020

    Diagnosing Fracture-Related Infection: Current Concepts and Recommendations.

    • GovaertGeertje A MGAMDepartment of Trauma Surgery, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands., Richard Kuehl, Bridget L Atkins, Andrej Trampuz, Mario Morgenstern, William T Obremskey, VerhofstadMichael H JMHJDepartment of Trauma Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands; and., Martin A McNally, Willem-Jan Metsemakers, and Fracture-Related Infection (FRI) Consensus Group.
    • Department of Trauma Surgery, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
    • J Orthop Trauma. 2020 Jan 1; 34 (1): 8-17.

    AbstractFracture-related infection (FRI) is a severe complication after bone injury and can pose a serious diagnostic challenge. Overall, there is a limited amount of scientific evidence regarding diagnostic criteria for FRI. For this reason, the AO Foundation and the European Bone and Joint Infection Society proposed a consensus definition for FRI to standardize the diagnostic criteria and improve the quality of patient care and applicability of future studies regarding this condition. The aim of this article was to summarize the available evidence and provide recommendations for the diagnosis of FRI. For this purpose, the FRI consensus definition will be discussed together with a proposal for an update based on the available evidence relating to the diagnostic value of clinical parameters, serum inflammatory markers, imaging modalities, tissue and sonication fluid sampling, molecular biology techniques, and histopathological examination. Second, recommendations on microbiology specimen sampling and laboratory operating procedures relevant to FRI will be provided. LEVEL OF EVIDENCE:: Diagnostic Level V. See Instructions for Authors for a complete description of levels of evidence.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…