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JPEN J Parenter Enteral Nutr · Sep 2019
Case ReportsKetoacidosis in Euglycemic Patients With Type 2 Diabetes After Abdominal Surgery.
- Ray Segebrecht, Michael Moncure, Ashley Bennett, Douglas Geehan, Charles W Van Way, and Lamont Weide.
- University of Missouri-Kansas City School of Medicine, Department of Internal Medicine, Kansas City, Missouri, USA.
- JPEN J Parenter Enteral Nutr. 2019 Sep 1; 43 (7): 937-940.
AbstractDiabetic ketoacidosis is defined as hyperglycemia >250 mg/dL with metabolic acidosis of arterial pH <7.3, serum bicarbonate <18 mEq/L with positive urine and serum ketones and an anion gap >10. Euglycemic ketoacidosis has been reported in patients with type 2 diabetes and in patients with type 1 diabetes. However, as a surgical complication, euglycemic ketoacidosis has not been reported. We report 2 cases from 2 teaching tertiary care centers of patients with type 2 diabetes who developed high-gap ketoacidosis in an intensive care unit while recovering from emergent abdominal surgery. Both patients developed altered mental status, metabolic acidosis with a bicarbonate level as low as 14 mEq/L, and an anion gap > 18, without hyperglycemia. Both patients had β-hydroxybutyrate levels > 5 mmol/L.© 2019 American Society for Parenteral and Enteral Nutrition.
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