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- Shun Nomura, Wataru Ishii, Ryosuke Hara, Shigeki Nanasawa, Kei Nishiwaki, Mitsuru Kagoshima, Tamaki Takano, Hidetoshi Satomi, and Tatsuya Usui.
- Division of Rheumatology, Department of Internal Medicine, Nagano Red Cross Hospital, Japan.
- Intern. Med. 2022 Apr 15; 61 (8): 1259-1264.
AbstractImmunoglobulin G4-related disease (IgG4-RD) is a systemic inflammatory disease characterized by infiltration of extensive IgG4-positive plasma cells and lymphocytes. Although IgG4-RD has been observed in almost all organs, it rarely affects the myocardium. Cardiovascular lesions of IgG4-RD appear as aortic (aortic aneurysm and aortitis) and pericardial (constrictive pericarditis) lesions as well as pseudotumors around the coronary arteries. We herein report a case of IgG4-RD with a cardiac mass in the right atrium involving a sinus node. This condition caused arrhythmia and repeated strokes. We successfully treated the patient through resection of the cardiac mass, catheter ablation and immunosuppressive therapy.
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