• Mun-Chun Yeap, Ching-Chang Chen, Chun-Ting Chen, Zhuo-Hao Liu, Chieh-Tsai Wu, Po-Chuan Hsieh, Hong-Yi Lai, Yu-Chi Wang, Ting-Wei Chang, Cheng-Chi Lee, Yu-Tse Liu, Yin-Cheng Huang, Kuo-Chen Wei, and Po-Hsun Tu.
• Department of Neurosurgery, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University, Taoyuan City, Taiwan.
• World Neurosurg. 2022 Jan 1; 157: e173-e178.

ObjectiveTo assess the predictive value of swab cultures of cryopreserved skull flaps during cranioplasties for surgical site infections (SSIs).MethodsA retrospective review was conducted of consecutive patients who underwent delayed cranioplasties with cryopreserved autografts between 2009 and 2017. The results of cultures obtained from swabs and infected surgical sites were assessed. The accuracy, sensitivity, and specificity of swab cultures for SSIs were evaluated.ResultsThe study included 422 patients categorized into two groups, swab and nonswab, depending on whether swab cultures were implemented during cranioplasties. The overall infection rate was 7.58%. No difference was seen in infection rates between groups. There were 18 false-positive and no true-positive swab culture results. All bacteria between swab cultures and SSI cultures were discordant. Meanwhile, there were 19 false-negative swab cultures. The results showed high specificity but low sensitivity for swab cultures to predict SSI occurrence and the pathogens.ConclusionsOwing to low accuracy and sensitivity, swab cultures of cryopreserved autografts should not be routinely performed during delayed cranioplasties.Copyright © 2021 Elsevier Inc. All rights reserved.

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