• Medicine · Oct 2021

    Meta Analysis

    Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials.

    • Lu-Kai Zhang, Fang-Bing Zhu, Huan-Huan Gao, Lei Zhang, and Ren-Fu Quan.
    • Department of Orthopaedics, Xiaoshan Traditional Chinese Medical Hospital, Hangzhou, Zhejiang Province, People's Republic of China.
    • Medicine (Baltimore). 2021 Oct 8; 100 (40): e27468e27468.

    BackgroundEffective postoperative analgesia is of great significance for postoperative rehabilitation. This meta-analysis aimed to investigate the efficacy of corticosteroid on pain following total joint arthroplasty.MethodPubMed (1996-December 2020), Embase (1996-December 2020), and the Cochrane Library (CENTRAL, December 2020) were searched and a total of 11 randomized controlled trials met our inclusion criteria.ResultsEleven randomized controlled trials met the inclusion criteria. Pooled data indicated the corticosteroid group was effective compared to the control group in terms of the visual analogue scale at rest (P < .05) and movement (P < .05), the total morphine equivalent consumption (P < .05), and the length of stay (P < .05), without increasing the risk of periprosthetic joint infection (P = .74) and the length of stay (P = .32).ConclusionsCompared to the control group, intraoperative corticosteroid was benefit to the pain management in total joint arthroplasty.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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