• Br J Anaesth · Aug 1992

    Thrombelastography after aspirin ingestion in pregnant and non-pregnant subjects.

    • C E Orlikowski, A J Payne, J Moodley, and D A Rocke.
    • Department of Anaesthetics, Faculty of Medicine, University of Natal, Durban, South Africa.
    • Br J Anaesth. 1992 Aug 1; 69 (2): 159-61.

    AbstractThe thrombelastograph (TEG) and bleeding time were performed before and 6 h after a single oral dose of aspirin 600 mg in a group of eight healthy volunteers and 12 pregnant patients. Measured TEG variables (r, k, r+k times and maximum amplitude) were unaltered after aspirin although there was a significant prolongation of the bleeding time in both groups. Although the TEG appeared not to detect aspirin-induced changes in platelet function, the TEG measures all phases of coagulation and the unaltered TEG after aspirin suggested a functioning coagulation system.

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