• Acta Derm. Venereol. · May 2019

    Review Case Reports

    Drug-induced Linear IgA Bullous Dermatosis: A Case Report and Review of the Literature.

    • Judith Lammer, Rüdiger Hein, Sophie Roenneberg, Tilo Biedermann, and Thomas Volz.
    • Department of Dermatology and Allergology, Technical University Munich, DE-80802 Munich, Germany.
    • Acta Derm. Venereol. 2019 May 1; 99 (6): 508-515.

    AbstractLinear IgA bullous dermatosis (LABD) is a rare subepidermal autoimmune blistering disease characterized by linear deposition of IgA along the basement membrane zone. Although most reported cases are idiopathic, there is a subset of patients with drug-induced LABD. Various drugs have been associated with the drug-induced form of the disease. This paper reviews the literature on drugs reported to elicit linear IgA dermatosis and its specific clinical presentation. In addition, a case report of a 77-year-old male patient with linear IgA dermatosis induced by vancomycin is described. The aim of this paper is to emphasize the need to include this differential diagnosis in cases of suspected adverse drug reactions, as well as to highlight the role of drugs in LABD.

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