• Leukemia & lymphoma · Apr 1999

    Case Reports

    T-cell-rich B-cell non-Hodgkin's lymphoma mimicking Hodgkin's disease.

    • B Bättig, E Mueller-Garamvoelgyi, S B Cogliatti, U Schmid, A Kappeler, T Cerny, J A Laissue, and M F Fey.
    • Institute of Medical Oncology, Inselspital, University of Berne, Switzerland.
    • Leuk. Lymphoma. 1999 Apr 1; 33 (3-4): 393-8.

    AbstractWe report on a patient with recurrent T-cell-rich B-cell lymphoma (TCRBCL), initially misdiagnosed as a lymphocyte-rich Hodgkin's disease. This case exemplifies the diagnostic problems of TCRBCL and the need for immunophenotypic analysis to differentiate TCRBCL from Hodgkin's disease, nodular paragranuloma and peripheral T-cell lymphoma. A rather unusual aspect is the long disease-free interval between the excision of the node in and the late relapse in 1996. The significance of the abundant T-cell infiltration in this B-cell neoplasm will be discussed and the concepts concerning antitumor response will be reviewed. Based on epidemiological data and the clinical behaviour TCRBCL does not seem to represent a distinctive pathological entity.

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