• Injury · Feb 2022

    Early versus delayed thromboprophylaxis with LMWH in pelvic-acetabular trauma- a prospective study.

    • Akshay Shetty, Sameer Aggarwal, Sandeep Patel, Siddharth Sharma, Karan Jindal, and Mahesh Prakash.
    • Senior Resident, Department of Orthopaedics, PGIMER, Chandigarh, INDIA.
    • Injury. 2022 Feb 1; 53 (2): 529-533.

    BackgroundDelayed presentation of pelvic-acetabular fractures is a common scenario in developing countries and there is usually a delay of more than 24 h in their presentation.ObjectivesWe aim to comparatively analyse early(<24 h) versus delayed (>24 h) thromboprophylaxis with low molecular weight heparin (LMWH) in prevention of deep venous thrombosis (DVT) in Pelvic Acetabular fractures.MethodsPatients of pelvic-acetabular fractures who presented during 1 year of study period were divided into 2 groups after exclusion of patients with contraindications for thromboprophylaxis. Group A included patients who received LMWH prophylaxis within 24 h of injury. Group B included patients who received LMWH prophylaxis after 24 h of injury. All patients underwent CT venography at day 14 and were followed up with doppler ultrasound on 4th and 8th week.Results110 patients with pelvic-acetabular fractures were included after exclusion of 61 patients. 4 out of 29 patients in group A (13.8%) and 12 out of 81 patients (14.8%) in group B developed DVT. There was no significant difference in incidence of DVT between Group A and B (P value-0.893).ConclusionThere was no difference between early and delayed thromboprophylaxis with LMWH in pelvic-acetabular trauma.Copyright © 2021. Published by Elsevier Ltd.

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