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Case Reports
Hypotension and bradycardia in infants after the use of topical brimonidine and beta-blockers.
- Nils K Mungan, Thomas W Wilson, Ken K Nischal, Gideon Koren, and Alex V Levin.
- Department of Ophthalmology, The Hospital for Sick Children, University of Toronto, Ontario, Canada.
- J AAPOS. 2003 Feb 1; 7 (1): 69-70.
AbstractBrimonidine is a selective alpha-2 adrenergic agonist used to treat glaucoma. There have been several reports of central nervous system depression after its use in infants. We observed rapid-onset bradycardia and decreased blood pressure in addition to central nervous system depression in 2 infants who received concomitant topical brimonidine and beta-blockers.
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