• AksoyDuygu YazganDYDepartment of Internal Medicine, Section of Endocrinology and Metabolism, Medical School, Hacettepe University, Ankara, Turkey., Arzu Gedik, Nese Cinar, Figen Soylemezoglu, Mustafa Berker, and Omer Alper Gurlek.
• Department of Internal Medicine, Section of Endocrinology and Metabolism, Medical School, Hacettepe University, Ankara, Turkey.
• J Res Med Sci. 2013 Nov 1; 18 (11): 1008-10.

AbstractThyroid disorders are frequently encountered. The diagnosis is straightforward unless clinical or laboratory findings are inconclusive and/or perplexing. Hyperthyroidism due to a thyrotropin-secreting pituitary adenoma rarely occurs and symptoms due to thyroid hormone excess are subtle. The presentation of the disease becomes unusual when co-secretion of other hormones with thyrotropin or concomitant thyroid parenchymal pathology exist. We present the case of a 63-year-old female patient with thyrotropinoma co-secreting growth hormone and multinodular goiter. She developed hyperthyroidism first due to thyrotropinoma and later due to a toxic nodule. Herein, we discuss the diagnostic and therapeutic challenges of hyperthyroidism with atypical presentation.

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