• A W Norasyikin, M Rozita, M J Mohd Johan, and Z Suehazlyn.
• Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM), Kuala Lumpur, Malaysia.
• Med Princ Pract. 2014 Jan 1; 23 (4): 387-9.

ObjectiveTo report an uncommon presentation of a rare case of autoimmune polyglandular syndrome type IIIb in an elderly woman.Clinical Presentation And InterventionA 62-year-old woman presented with anaemic symptoms and jaundice. Blood tests showed macrocytic anaemia due to vitamin B12 deficiency with Coombs negative haemolysis. A thyroid function test was consistent with hypothyroidism. Autoimmune antibody assays were positive for anti-parietal cell, anti-intrinsic factor and anti-thyroid peroxidase antibodies. A final diagnosis of autoimmune thyroiditis with pernicious anaemia, which constituted autoimmune polyglandular syndrome type IIIb, was made and the patient was treated with L-thyroxine, vitamin B12 injection and a blood transfusion. She was discharged uneventfully after a week of hospitalization.ConclusionThis case showed that the presence of one autoimmune endocrine disease should prompt clinicians to look for other coexisting autoimmune diseases which may be asymptomatic despite positive autoantibodies.© 2014 S. Karger AG, Basel

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